Sexual Health
PT-141
Libido and Arousal Research, Centrally Acting
Flat $35 tracked shipping10mg per vial
$140 USD
Add 2 more, unlock 19%
| Test | Result | Verdict |
|---|---|---|
| Purity, HPLC | 99.12% | PASS |
| Identity, LC-MS | 1025.2 Da | PASS |
| Sterility | No growth | PASS |
| Endotoxin | Within limit | PASS |
| Heavy metals + fentanyl | Not detected | PASS |
Shipping, delivery and guarantee terms
- Shipping
- Flat $35, tracked worldwide to supported markets
- Delivery
- 5 to 10 business days, guaranteed
- Payment
- Card, bank transfer, or crypto · All sales final except a purity failure
- Included
- 60-day money-back guarantee · Third-party batch COA
The short answer
What is PT-141 (bremelanotide)?
PT-141, also called bremelanotide, is a melanocortin receptor agonist studied for low libido and sexual arousal in both men and women (Molinoff et al., 2003). Unlike erectile-dysfunction medications that work on blood flow, it acts centrally, on arousal pathways in the brain, which is why it has been studied for desire rather than mechanics alone. The phase 3 RECONNECT trials in premenopausal women used a single fixed 1.75 mg subcutaneous dose taken as needed rather than daily (Kingsberg et al., 2019), and bremelanotide is the active ingredient in the FDA-approved product Vyleesi. Peptara supplies research-grade PT-141 as a lyophilized 10mg vial for laboratory research; the figures here describe what published studies reported, not a dose for any person, and a qualified clinician sets any personal plan.
The Science
Arousal That Starts in the Brain
Most well-known performance medications work on blood flow. PT-141 takes a different route entirely, acting on melanocortin receptors in the central nervous system that govern desire and arousal. That is why it has been studied for both men and women.
Central Mechanism
Acts on brain arousal pathways rather than on blood vessels.
Both Sexes
Studied in men and women, with an FDA-approved version for women.
Desire, Not Just Function
The studied endpoints are libido and arousal, which is a different mechanism from blood-flow medications.
Applications
Common Use Cases
Low Libido
Reduced desire is the research area, in both sexes, where the central mechanism is the one studied.
Arousal Support
Studied for arousal that begins with desire rather than blood flow alone.
Couples Use
Reported anecdotally rather than studied. No trial measured couples as a unit.
As-Needed Tool
The trials dosed it as needed rather than daily, which is the published pattern.
Dosage as studied
What doses did PT-141 studies use?
The clearest PT-141 dosing figure comes from the phase 3 RECONNECT trials in premenopausal women, which used a single fixed 1.75 mg subcutaneous dose taken as needed rather than on a daily schedule (Kingsberg et al., 2019). Earlier research explored other routes and populations: a placebo-controlled dose-finding trial evaluated bremelanotide in premenopausal women (Clayton et al., 2016), and an early double-blind study assessed an intranasal form of PT-141 in healthy men and men with mild-to-moderate erectile dysfunction (Diamond et al., 2004).
| Study or setting | Population | What it reported about dosing | Source |
|---|---|---|---|
| Phase 3 RECONNECT | Premenopausal women | A single fixed 1.75 mg subcutaneous dose, taken as needed rather than daily | Kingsberg et al., 2019 |
| Phase 2 dose-finding | Premenopausal women | A placebo-controlled evaluation across a range of doses | Clayton et al., 2016 |
| Early PK/PD study | Healthy men and men with mild-to-moderate ED | Evaluated an intranasal form of PT-141 | Diamond et al., 2004 |
| Vyleesi label | FDA-approved use | Carries a dosing-frequency cap, the only regulated frequency guidance | Vyleesi Prescribing Information |
There is no PT-141 dosage chart or calculator that converts these study figures into a personal dose. A lyophilized 10mg research vial is reconstituted with bacteriostatic water, and the reconstitution calculator on this site reports concentration in units rather than mL. For the full breakdown of what the trials reported, see the PT-141 dosage page. Picking a dose is a decision for a licensed clinician, not something to copy from a trial protocol.
Nasal spray vs injection
Is PT-141 a nasal spray or an injection?
Both forms appear in the research record, which is why searches split between a PT-141 nasal spray and an injection. The earliest clinical work used an intranasal formulation, studied in healthy men and men with mild-to-moderate erectile dysfunction (Diamond et al., 2004). Development later moved to subcutaneous injection: the FDA-approved product Vyleesi is delivered subcutaneously, and the phase 3 RECONNECT trials used a subcutaneous dose (Kingsberg et al., 2019).
Peptara supplies research-grade PT-141 as a lyophilized powder in a sealed 10mg vial, not as a pre-mixed nasal spray or a ready-to-use pen. How reconstituted material is handled is a laboratory matter, and any route of administration in people is a conversation for a licensed clinician.
Protocol Guidance
What the as-needed trials reported
Protocol Guidance
What the as-needed trials reported
Research timeline
What the as-needed trials reported
The trial dose
The RECONNECT phase 3 trials used a single fixed 1.75 mg subcutaneous dose, taken as needed rather than daily (Kingsberg et al., 2019).
Label caps
The approved product Vyleesi carries dosing frequency caps on its label, which is the only regulated frequency guidance that exists for this molecule (Vyleesi Prescribing Information).
Reported effects
Nausea and facial flushing were among the most commonly reported effects in the trial programme, reported as dose related (Kingsberg et al., 2019).
Research grade
Bremelanotide is the active ingredient in Vyleesi, so the names point to the same molecule. Research-grade PT-141 is sold for laboratory research and is not the approved product.
Your Kit
What's Included
$140 USD
Flat $35 shipping · All sales final
PT-141 10mg Vial
10mg per vial · Lyophilized powder, sealed vial
Study Protocol Reference
The as-needed trial dose and label caps, as published
Worldwide Shipping
5 to 10 business days, guaranteed
Ongoing order support
Direct team access
Your kit includes the vials and bacteriostatic water. Insulin syringes ship to select delivery regions; where they can't ship, we send a same-day sourcing link. A printed reference guide ships with every order.
Traveling with your order
Freeze-dried vials travel well; reconstituted vials travel cold. Rules vary by country. Share your dates when you order.
Why your vials arrive plain
Unlabeled on purpose: discreet, and standard for research-grade material. Match a batch to its certificate with your order number. See the COA page.
Verified orders
What buyers said about their PT-141 (Bremelanotide) order
5.00 · 9 reviews from orders containing this vial. Published word for word.
box was fine labels straight both vials sealed clean. mt2 clear pt141 clear foam snug no rattling when i shook it. done
Nguyen Thi Linh - Brisbane
Verified order · MT-2 (Melanotan-2), PT-141 (Bremelanotide) · Aug 25, 2026
I landed in vietnam for work and within a week peptara ads were showing up on my facebook feed which felt almost creepy until i actually looked into it. research was solid, third party testing posted publicly, and the support chat answered me at like 1am their time. ordered two vials to start
Anonymous - Hoi An
Verified order · Epithalon, PT-141 (Bremelanotide) · Aug 16, 2026
solid as expected. nothing to add really
Anon - Hoi An
Verified order · PT-141 (Bremelanotide), Glutathione · Aug 10, 2026
one thing i want to highlight is that their team actually walked me through the research side of pt141 instead of just selling it to me. showed me the study, told me where the data was weak, answered every single question i threw at them over two days of back and forth before i committed to buying
Anonymous - Cần Thơ
Verified order · Selank, PT-141 (Bremelanotide) · Aug 06, 2026
one thing that caught my eye was the receipt tape had a slightly different shade than what i got in may but that is it. everything else checked out, both vials sealed properly with clear liquid and the foam held them without any movement when i rotated the tray. batch numbers matched the site under normal desk light
R. - Miami, FL
Verified order · BPC-157, PT-141 (Bremelanotide) · Jul 10, 2026
fine as far as i am concerned, nothing rattled or shifted in transit
Anon - Hoi An
Verified order · PT-141 (Bremelanotide), Glutathione · Jul 05, 2026
Our Guarantee
We Stand Behind Our Quality.
Peptara Labs supplies research-grade PT-141 (Bremelanotide), third-party tested with a Certificate of Analysis on every batch. The guarantee is on the material and on how the order is handled. It is not a guarantee of any outcome.
60-Day Money Back Guarantee
Test it at any lab, or your money back
Send any vial to an independent lab within 60 days of delivery. If it does not test as stated on its certificate of analysis (COA), or your order was not handled correctly, you get a full refund. The 60 days is your window to verify us, not a shelf life. The guarantee is on product quality, never on a health outcome.
Study Protocol Reference, Included
Every order includes a written reference to the dose ranges published studies used, with the study named, plus support at no extra cost. This is not a prescription; consult a licensed physician.
Direct WhatsApp Access
Every order includes direct access to our support team. Questions about certificates, reconstitution, storage, shipping or an order, message us any time and a real person responds.
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Quality guarantee: full refund on any purity failure. All sales otherwise final. The 60-day money back guarantee covers product purity, certificate of analysis, and fulfillment. It is not conditioned on any outcome and does not promise one. This is educational information, not medical advice; consult a licensed physician.
Also in a kit
PT-141 (Bremelanotide) is in a research kit
A kit groups catalog compounds from one research area and is priced at 35 percent off their combined retail. It is a grouping for browsing related research, not a protocol, and no kit has been tested as a combination.
Pantheon kit
Multi-system research
Retatrutide, Tesamorelin, MOTS-c, TB-500, BPC-157, CJC-1295 / Ipamorelin, Glutathione, KLOW Combo, GHK-Cu, PT-141 (Bremelanotide)
Research and citations
Peer-reviewed sources
- Kingsberg SA, et al. (2019). Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials. Obstetrics and Gynecology. doi.org/10.1097/AOG.0000000000003500
- Clayton AH, et al. (2022). Safety Profile of Bremelanotide Across the Clinical Development Program. Journal of Women's Health. doi.org/10.1089/jwh.2021.0191
- Pfaus JG, Sadiq A, Spana C, Clayton AH. (2022). The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder in premenopausal women. CNS Spectrums. doi.org/10.1017/S109285292100002X
Citations refer to the peer-reviewed publications these figures are taken from. Every dose range reported on this site is the range a named study used. Not a substitute for medical advice.
Explore more
Related guides, comparisons, and compounds studied for related endpoints
PT-141 complete guide
Central mechanism, the FDA-approved context, dosing, and side effects.
MT-2
Related melanocortin peptide used for tanning.
Reconstitution calculator
Concentration math for a lyophilized vial, in units rather than mL.
Peptara FAQ
Sourcing, COAs, cold-chain, and payment questions answered.
About Peptara
Who we are and how we source and test.
Research kits
Five named kits grouped by research area, each at 35% off combined retail.
PT-141 Dosage
PT-141 For Libido
PT-141 Half Life
PT-141 Side Effects
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Where PT-141 sits among peptides studied for desire and arousal.
PT-141 FAQ
Interested in PT-141?
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Order Now · $140 USDCertificate of analysis included · Order support on WhatsApp · Tracked worldwide shipping